Vessels discovered in the brain that were thought not to exist could revolutionise study of neurological diseases like Alzheimer's.
The brain is directly connected to the immune system by vessels previously thought not to exist, new research reports. The finding means the textbooks will have to be rewritten. Discovery of the vessels may also revolutionise the study of neurological diseases like Alzheimer's and autism.
The left-hand image below shows the old map of the lymphatic system, and the updated version is on the right.
The discovery will likely have profound implications for how scientists study the neuro-immune system, Professor Kipnis said: "Instead of asking, 'How do we study the immune response of the brain?' 'Why do multiple sclerosis patients have the immune attacks?' now we can approach this mechanistically.
Because the brain is like every other tissue connected to the peripheral immune system through meningeal lymphatic vessels.
It changes entirely the way we perceive the neuro-immune interaction. We always perceived it before as something esoteric that can't be studied. But now we can ask mechanistic questions.
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